Caleb J. Gammon

Caleb J. Gammon

Bonetto Lab, Department of Pathology, CU Anschutz Medical Campus.

Experimental biologist at CU Anschutz. I build the analysis and automation that research groups and small operations actually run on.

Background

I work in the Bonetto Lab at the CU Anschutz Medical Campus, in the Department of Pathology. The lab studies cancer cachexia, the musculoskeletal wasting that accompanies cancer. I joined in August 2024 and was promoted to Senior Research Services Professional in December 2025.

I am the group's only computational scientist. I own the bulk RNA-seq and the single-cell and single-nucleus analysis, from quality control through biological interpretation, pathway analysis, and reproducible reporting. I also run lab operations: purchasing and inventory, vendor coordination, equipment readiness, experiment scheduling, SOP authoring, and training for researchers and clinical fellows.

I still work at the bench, so I usually know how the data I am analyzing was produced. That work includes mammalian cell culture with both primary and immortalized lines, 96-well phenotypic workflows, transfection, ELISA, Western blot, qPCR, microscopy, and nucleic-acid and protein extraction. I have six years of research experience.

Before this I was a Lab Researcher in the Seibold Lab at National Jewish Health, from May 2020 to July 2024, working on airway epithelial biology and asthma genomics. I cultured primary human airway epithelial cells at air-liquid interface, operated Beckman Coulter Biomek i7 liquid-handling automation for high-throughput extraction, NGS library prep, and qPCR, and worked on GeoMx DSP spatial transcriptomics.

Outside the lab I build production automation for a marine service company in South Florida: a constraint-based field-work scheduler and an automated weekly invoicing pipeline. Both run against real operations, so the interesting part is not the model. It is what happens when the input is wrong.

  • Python
  • R
  • Bash
  • JavaScript / Node.js
  • Git
  • CP-SAT / OR-Tools
  • Docker
  • Railway
  • Snakemake
  • Seurat
  • scanpy
  • DESeq2
  • Cellpose
Positions
Senior Research Services Professional, Bonetto Lab, CU Anschutz (Pathology)
2024-08 -- present
Lab Researcher, Seibold Lab, National Jewish Health
2020-05 -- 2024-07
Education
MBA, Entrepreneurship, University of Colorado Denver (in progress)
2025-01 -- present
B.A. Molecular, Cellular and Developmental Biology, University of Colorado Boulder
2023
B.A. Neuroscience, University of Colorado Boulder
2023
Talks and recognition
Abstract Competition Winner and Conference Speaker, National Jewish Health Research Retreat
2024
Co-first author presentation, Cancer Cachexia Conference, Turin
2025
Poster, Muscle Biology and Cachexia Conference, Houston
2025
Publications
  1. 2026

    An FGF21-IGFBP1 tumor-liver relay drives musculoskeletal defects in colorectal cancer cachexia.

    Huot JR, Kamdar UR, Gammon CJ, Livingston PD, Pin F, Jamnick NA, Weinzierl NM, Callaway CS, Roberson PA, Essex AL, Xu J, Cardona LFP, Devereaux MW, Anderson AL, Shearn CT, Sokol RJ, Lee S, Gao B, Boorgula MP, Goodspeed A, Novinger LJ, Adams DJ, Bonetto A.

    Nature Communications. 2026. 10.1038/s41467-026-77305-6

  2. 2026

    Chemotherapy induces tissue NAD+ loss, and downregulation of NAD+ biosynthetic enzyme Nrk2 marks muscle wasting.

    Pollanen N, Gammon CJ, Pin F, et al.

    bioRxiv. 2026. Preprint 10.64898/2026.07.11.736679

  3. 2026

    MOTS-c partially protects against skeletal muscle deterioration in C26 cachexia.

    Jamnick NA, Livingston PD, Gammon CJ, Weinzierl NM, Novinger LJ, Bonetto A.

    Frontiers in Medicine. 2026;13:1838178. 10.3389/fmed.2026.1838178

  4. 2025

    Vincristine impairs musculoskeletal development in pediatric mice.

    Jamnick NA, Livingston PD, Gammon CJ, Weinzierl NM, Novinger LJ, Adams DJ, Bonetto A.

    BMC Cancer. 2025;25(1):1782. 10.1186/s12885-025-15262-x

  5. 2025

    B0092 tumor-bearing mice are a new model for the study of cachexia in head and neck cancer.

    Livingston PD, Labbate Bonaldo AL, Jamnick NA, Weinzierl NM, Gammon CJ, Callaway CS, Lee S, Gao B, Goodspeed A, Carvalho RF, Young CD, Orlicky DJ, Adams DJ, Novinger LJ, Bonetto A.

    American Journal of Physiology: Cell Physiology. 2025;329(2):C646-C658. 10.1152/ajpcell.00374.2025

Listed newest first. The Nature Communications paper has no volume or article number assigned yet.

Resume and code

The resume has the full method and instrument list. Project code is on GitHub.

Resume PDF GitHub